For most people, the second dose should be given 2 to 6 months after the first dose. Shingles vaccine is given as a two-dose series. Adults 19 years and older who have a weakened immune system because of disease or treatments.Recombinant shingles vaccine is recommended for: By preventing shingles, recombinant shingles vaccine also protects against PHN and other complications. Recombinant shingles vaccine provides strong protection against shingles. Shingles cannot be passed from one person to another, but the virus that causes shingles can spread and cause chickenpox in someone who has never had chickenpox or has never received chickenpox vaccine. After you have chickenpox, the virus stays in your body and can cause shingles later in life. Shingles is caused by varicella-zoster virus, the same virus that causes chickenpox. People with weakened immune systems also have a higher risk of getting shingles and complications from the disease. An older adult with shingles is more likely to develop PHN and have longer lasting and more severe pain than a younger person. The pain from PHN can be severe and debilitating. PHN occurs in the areas where the shingles rash was and can last for months or years after the rash goes away. The most common complication of shingles is long-term nerve pain called postherpetic neuralgia (PHN). Rarely, shingles can lead to complications such as pneumonia, hearing problems, blindness, brain inflammation (encephalitis), or death. In addition to the rash, shingles can cause fever, headache, chills, or upset stomach. Shingles (also called herpes zoster, or just zoster) is a painful skin rash, usually with blisters. Recombinant zoster (shingles) vaccine can prevent shingles.
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